Dynamics of nucleosomes and elongation complexes

We apply molecular simulation methods to study the dynamics of nucleosomes and elongation complexes in collaboration with Laboratory of transcription regulation and replication headed by Prof. V. Studitsky.

Project team:

Current research topics:

  • MD simulations and covariance analysis of nucleosome unfolding
  • Molecular basics for asymmetric binding of H2A-H2B dimers in nucleosome
  • Nucleosome and H1 interactions
  • Molecular models of Pol II-nucleosome interactions

Some simulation results: